Journal of Clinical and Medical Images (ISSN 2640-9615)

Volume 5

Diffuse Osteolytic Metastases of Prostate Adenocarcinoma

1. Clinical Image A 52-year-old man presented with a 2-month history of low back pain. Computed tomography (CT) of thoracolumbar spine showed diffuse osteolytic bone metastases (Figure 1). Physical examination revealed a digital rectal exam compatible with frozen pelvis. His prostate-specific antigen (PSA) was 4935 ng/ml. A prostate biopsy was done, and the subsequent histology […]

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Noninvasive Mechanical Ventilation of Critically Ill Patients in ICUs in Mainland China: A Cross-Sectional Study

1. Abstract Although noninvasive mechanical ventilation (NIV) has been very common used for ICU patients, limited information exists about the epidemiological information of NIV in mainland China. This is a cross-sectional study in which patients with NIV were observed in September, 2012 from 15 ICUs. Epidemiological data and clinical outcomes were assessed among those who

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The Neural Pleonastics- Neurofibroma

1. Preface Neurofibroma is a fairly prevalent, benign, peripheral nerve sheath tumour composed of Schwann cells, fibroblasts, perineurial cells and mast cells disseminated within a variably myxoid or collagenous stroma. Neuronal element of transformed Schwann cells is admixed with non- neoplastic, fibrous element constituted of fibroblasts. Neurofibroma is generally engendered by chromosomal mutations within the

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Lactoferrin as Potential Treatment Oral Submucous Fibrosis: A Review Article

1. Abstract 1.1. Background: Oral submucous fibrosis (OSMF) is a chronic disease of oral mucosa characterized by inflammation and progressive fibrosis of lamina propria and deeper connective tissues, followed by stiffening of an otherwise yielding mucosa resulting in difficulty in opening the mouth. Etiology of OSMF was excessive use of areca nut and its flavored

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The Role of MCU Expression Regulation in Pathogenesis

1. Abstract Mitochondrial calcium uniporter is an intensively investigated calcium channel, its molecule components, structure features and gene encoding have been explored for a long time. Through the researches, the further findings illustrate that mitochondrial calcium unidirectional transporter (MCU) is a macromolecular complex related to regulate the calcium of Intracellular and extracellular. Based? on our

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One-Stage Closure of Venous Ulcers with Matriderm and Split-Thickness Skin Grafts

1. Abstract Venous ulcers are important cause of chronic wounds with high hospitalization costs associated. Compression therapy alone, as the mainstay treatment, often fails to completely close large ulcers which require surgery. Bi-layered constructs of dermal matrix and split-thickness skin-graft are already widely used in burns, scar resurfacing, traumatic wounds and diabetic ulcer, but rarely

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Pleomorphic Adenoma of the Breast with Atypical Hyperplasia May Originate from Progenitor Cells: A Case Report and Review of the Literature

1. Abstract 1.1. Aims: Pleomorphic adenoma (PA) of the breast in association with severe atypical hyperplasia is exceedingly rare, and supports the opinion that breast PA is not always benign. We report a case of breast PA with severe atypical hyperplasia of squamous epithelium and discuss its histological origin, morphological characteristics, and biological behavior. Methods

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Upper Intestinal Gastrointestinal Bleeding from Fish Bone Foreign Body in The Pharynx: Radiological Study, Management and Removal of the Foreign Body

1. Clinical Image Fish Bone Foreign Body impaction in the upper aerodigestive tract is a common cause of access to emergency room [1]. One of the sites of impact is pharynx. FFB are difficult to identify on plain radiography, depending on their size, bone calcification, and the type of fish. Computed tomography (CT) is the

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Preliminary Results of Tocilizumab and Interferon α-2β Treatment of SARS-CoV-2

1. Abstract Seven patients receiving Hydroxychloroquine (HCQ) and Zinc (Zn) for CoVid-19 with PCR positive results were admitted to hospital after failing to improve. Following NCT04349410 protocol and failure to improve with elevated interleukin-6 and ferritin levels, patient’s treatment was changed following measurement of Corona Virus Pneumonia (CVP). Follow up measurements of CVP confirmed improvement

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Fleming Inflammation and Cardiovascular Disease SARS-CoV-2 Proposed Treatment Protocol. Initial COVID Hydroxychloroquine Failure Responds to Interferon α-2β and Tocilizumab

1. Abstract Currently there is no established treatment protocol for SARS-2 (CoVid-19). Proponents of hydroxychloroquine (HCQ) argue that early intervention may sufficiently prevent replication of the virus and avoid the need for hospitalization. In instances where viral replication continues and the patient develops CoViD pneumonia (CVP), such patients – particularly with comorbidities – are prone

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