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Homocysteine is a sulfhydryl-containing amino acid formed during the metabolism of methionine. Recent evidence links elevated homocysteine levels to thrombosis via several mechanisms such as increased tissue factor expression, attenuated anticoagulant processes, enhanced platelet reactivity, increased thrombin generation, augmented factor V activity, impaired fibrinolytic potential, and vascular injury, including endothelial dysfunction [1-4]. Thus, higher total …

Treatment of Venous Thrombosis in Young Patient with Moderately Severe Homocysteinemia – is Long Term Anticoagulation with Direct Oral Anticoagulation Effective Along with Folate and B12 Supplementation Read More »

1. Abstract 1.1. Introduction: Cortical laminar necrosis (CLN) corresponds to neuronal ischemic remodeling secondary to hypoxia. In the past, it was underdiagnosed and unrecognized. Nowadays, thanks to the accessibility of MRI, it is now possible to make the diagnosis of CLN in tropical environments.

1. Abstract Fish bone induce the perforated appendicitis is a very rare condition, that requires diagnosis and surgery as soon as possible. We report the unusual case of a 42-year-old male patient, had suddenly felt an abdominal pain at the right iliac fossa gradually increased about 8 hours before hospitalization.

1. Abstract 1.1. Introduction and Importance: SCHMID metaphyseal chondrodysplasia is a rare cause of short stature with a good prognosis regarding other types of chondrodysplasia in reason of the normal integrity of the growth plate.

1. Abstract Vaughan Jackson Syndrome is described as a disruption of the digital extensor tendons, beginning on the ulnar side of the hand  and wrist with the Extensor Digiti Minimi and Extensor Digitorum Communis (EDC) tendon of the small finger. If the underlying pathology is not treated, sequential rupture of the EDC tendons of the …

Vaughan Jackson Syndrome in Uncontrolled Rheumatoid Arthritis: RA Patient with Sudden Loss of Use with the Hands Read More »

1. Abstract A 59-year-old male presented to our hospital with a 6-month history of abdominal pain and altered bowel habits. Clinically he had a palpably hard liver. An abdominal and pelvis CT scan showed a rectosigmoid tumor with multiple liver metastasis. Sigmoidoscopy showed a large tumor causing almost complete luminal obstruction.