Treatment of Venous Thrombosis in Young Patient with Moderately Severe Homocysteinemia – is Long Term Anticoagulation with Direct Oral Anticoagulation Effective Along with Folate and B12 Supplementation
Homocysteine is a sulfhydryl-containing amino acid formed during the metabolism of methionine. Recent evidence links elevated homocysteine levels to thrombosis via several mechanisms such as increased tissue factor expression, attenuated anticoagulant processes, enhanced platelet reactivity, increased thrombin generation, augmented factor V activity, impaired fibrinolytic potential, and vascular injury, including endothelial dysfunction [1-4]. Thus, higher total […]