Journal of Clinical and Medical Images (ISSN 2640-9615)

Author name: Clinical and Medical Images

Quantitative Assessment of Airway Wall Thickening in Combined Pulmonary Fibrosis and Emphysema Patients According to Cumulative Cigarette Smoking

1. Abstract 1.1. Purpose: The aim of this study was to evaluate role of Pi10 as a clinically relevant biomarker of smoking-related airway injury in patients with Combined Pulmonary Fibrosis and Emphysema (CPFE) in CT according to cumulative cigarette smoking. 1.2. Material and Methods: We retrospectively assessed 54 CPFE patients and 18 healthy non-smokers (control) […]

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Hypophosphatasia: Another Possible Cause of Periarticular Swelling?

1. Introduction Hypophosphatasia is a rare genetic metabolic disease caused by mutations of the ALPL gene, which encodes the tissue nonspecific alkaline phosphatase (TNSALP). The most important HPP’s biochemical marker are a low activity of the serum ALP, high urine PEA and serum pyridoxal phosphate (PLP) [1]. The HPP onset can occur at any age

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Delayed Presentation of Ischemic Stroke After COVID-19 Pneumonitis. How Late Can It Present? – An Interesting Case Report and A Review of Current Evidence

1. Abstract Coronavirus disease 2019 (COVID-19) pandemic has now become a major public health concern throughout the world. Although symptoms in majority of patients are due to involvement of respiratory system, it is not unusual for other organ systems to be involved too. Micro vascular and macro vascular complications associated with this disease, contributing to

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Correlation of Preoperative Axillary Lymph Node Status to Final Histology After Axillary Surgery for Breast Cancer

1. Abstract 1.1. Introduction: Axillary lymph node(ALN) status is an important prognostic factor for breast cancer. The high accuracy of axillary ultrasound(AUS) has led to several ongoing trials where sentinel lymph node biopsy(SLNB) omission is explored for negative AUS in early breast cancer. We aimed to correlate pre-operative ALN status with final histology. Specifically, we

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Diffuse Osteolytic Metastases of Prostate Adenocarcinoma

1. Clinical Image A 52-year-old man presented with a 2-month history of low back pain. Computed tomography (CT) of thoracolumbar spine showed diffuse osteolytic bone metastases (Figure 1). Physical examination revealed a digital rectal exam compatible with frozen pelvis. His prostate-specific antigen (PSA) was 4935 ng/ml. A prostate biopsy was done, and the subsequent histology

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Noninvasive Mechanical Ventilation of Critically Ill Patients in ICUs in Mainland China: A Cross-Sectional Study

1. Abstract Although noninvasive mechanical ventilation (NIV) has been very common used for ICU patients, limited information exists about the epidemiological information of NIV in mainland China. This is a cross-sectional study in which patients with NIV were observed in September, 2012 from 15 ICUs. Epidemiological data and clinical outcomes were assessed among those who

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The Neural Pleonastics- Neurofibroma

1. Preface Neurofibroma is a fairly prevalent, benign, peripheral nerve sheath tumour composed of Schwann cells, fibroblasts, perineurial cells and mast cells disseminated within a variably myxoid or collagenous stroma. Neuronal element of transformed Schwann cells is admixed with non- neoplastic, fibrous element constituted of fibroblasts. Neurofibroma is generally engendered by chromosomal mutations within the

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Lactoferrin as Potential Treatment Oral Submucous Fibrosis: A Review Article

1. Abstract 1.1. Background: Oral submucous fibrosis (OSMF) is a chronic disease of oral mucosa characterized by inflammation and progressive fibrosis of lamina propria and deeper connective tissues, followed by stiffening of an otherwise yielding mucosa resulting in difficulty in opening the mouth. Etiology of OSMF was excessive use of areca nut and its flavored

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The Role of MCU Expression Regulation in Pathogenesis

1. Abstract Mitochondrial calcium uniporter is an intensively investigated calcium channel, its molecule components, structure features and gene encoding have been explored for a long time. Through the researches, the further findings illustrate that mitochondrial calcium unidirectional transporter (MCU) is a macromolecular complex related to regulate the calcium of Intracellular and extracellular. Based? on our

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One-Stage Closure of Venous Ulcers with Matriderm and Split-Thickness Skin Grafts

1. Abstract Venous ulcers are important cause of chronic wounds with high hospitalization costs associated. Compression therapy alone, as the mainstay treatment, often fails to completely close large ulcers which require surgery. Bi-layered constructs of dermal matrix and split-thickness skin-graft are already widely used in burns, scar resurfacing, traumatic wounds and diabetic ulcer, but rarely

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