Clinical Image

1. Abstract This case report presents a 23-year-old male patient with genera lized anterior spacing, managed using a minimally invasive approach with the Bioclear matrix system and Omnichroma composite (OPA2 shade). The treatment aimed to enhance aesthetics without tooth preparation. The patient was followed for one year, showing excellent aesthetic results and stability with no

1. Abstract This case report presents a 23-year-old male patient with generalized anterior spacing, managed using a minimally invasive ap proach with the Bioclear matrix system and Omnichroma composite (OPA2 shade).

1. Introduction Sickle-cell disease (SCD) is one of the most common severe monogenic disorders in the world with haemoglobin polymerisation resulting in multiple systemic complications including nephropathy [1].

1. Abstract Ovarian torsion [OT] is a rare but serious condition in pediatric patients, with an incidence of 4.9–20/100,000. It may arise due to ovarian masses, elongated ligaments, or structural hypermobility, potentially leading to the loss of reproctive potential if not managed effectively.

1. Abstract 1.1. Background and Objective: Nodal Osteoarthritis (NOA) is known as cartilage loss disease in hand-finger joints that relates to the production many of inflammatory responses. The objective of this study was to determine the role serum leptin level in the deve lopment of nodal osteoarthritis disease.

1. Clinical Image A 76-year-old male presented to the emergency department with one year of generalized weakness, 20 lbs weight loss, and physical deconditioning. In the preceding one month he had developed a non-tender and non-pruritic widespread nodular erythematous rash, seen in Fig. 1, 2, and 3.