Maximising Efficiency of Spatial Transcriptomics in Scleroderma: Challenges and Opportunities
Scleroderma (SSc) is a chronic, multi-system, auto-immune me diated disease that impacts up to 240 million people worldwide [1].
Volume 8
Etonogestrel Subdermal Implant in Adolescents: Everything We Should Know to Conduct Proper Counselling
1. Abstract Sexual education and access to contraceptives are crucial in re ducing the economic, health, and social burdens of unplanned pregnancies among adolescents. Adolescence, defined by the World Health Organization (WHO) as the transition period between childhood and adulthood, spans from ages 10 to 19.
A Case of Prostate Cancer with Multiple Bone Metastases in which Standard Treatment was Ineffective but Remission was Achieved with Amplified Natural Killer Cell Therapy, and the Usefulness of PD-L1 Positivity as a Biomarker for Solid Tumors
1. Abstract Amplified natural killer (ANK) therapy is a treatment that improves the safety and efficacy of the original (LAK) immunotherapy.
From Belly to Bedside: The Gut Microbiota’s Influence on Septic Shock: A Review Article
https://doi.org/10.47829/JCMI.2024.8606 The gut microbiota and sepsis are closely related, and there has been increased research recently on the role that microbial dysbiosis plays in the development of sepsis.
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Complicated Acute Pancreatitis Onset after Immune Checkpoint Inhibitor Treatment – A Case Report
1. Abstract Hodgkin lymphoma is a haematological type of cancer. Lately, immune checkpoint inhibitors (ICI) have become a part of the wide therapeutic arsenal targetting this disease. Even though they have promissing results, they are also associated with a great range of adverse events.
AGI In Radiation Oncology – The Dawn of New Era
1. Review Artificial General Intelligence has kept its footsteps in the field of Radiation Oncology. Radiation delivery consists of 5 major steps (Figure 1), i.e a) Patient assessment which includes Radia- tion Decision and consultation ,b) Simulation consisting of Image Registration and Reconstruction and Contouring , c).
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Contrast Enema for Neonatal Distal Bowel Obstruction: The Diagnostic and Pathological Yield
https://doi.org/10.47829/JCMI.2024.8409 Neonatal distal bowel obstruction (DBO) can present a diagnostic challenge [1, 2] As different aetiologies have similar clinical mani festations with not all surgical intervention [2, 3]. Contrast enemas (CE) can help differentiate the aetiology avoiding the need for sur gery [2-4]. We reviewed 20years of CE to evaluate their diagnostic and pathological yield
Cerebral Venous Thrombosis as a Rare Etiology of Spontaneous Subarachnoid Hemorrhage: A Case Study
1. Abstract 1.1. Background Spontaneous or non-traumatic subarachnoid hemorrhage is pre dominantly attributed to the rupture of an aneurysm, accounting for 85% of cases, while non-aneurysmal peri mesencephalic he morrhage constitutes approximately 10%. Although rare, cerebral venous thrombosis can also lead to subarachnoid hemorrhage, presenting clinical and radiological signs that may closely resemble those of
Leptin Hormone Level Effect on the Nodal Osteoarthritis Patients
1. Abstract 1.1. Background and Objective: Nodal Osteoarthritis (NOA) is known as cartilage loss disease in hand-finger joints that relates to the production many of inflammatory responses. The objective of this study was to determine the role serum leptin level in the deve lopment of nodal osteoarthritis disease.
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Co-Existence of NMDAR Encephalitis with Multiple Sclerosis: A Case Report
1. Abstract NMDAR (N-methyl-D-aspartate receptor) encephalitis is common auto-immune encephalitis. There are references with overlap with demyelinating diseases.
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